It is a strong chaotropic agent, meaning it disrupts the structure of proteins and nucleic acids by disrupting hydrogen bonding and hydrophobic interactions. Guanidine thiocyanate is often used in nucleic acid isolation protocols, particularly in the extraction of RNA from cells or tissues. Its ability to denature proteins and inhibit ribonucleases helps to preserve RNA integrity during the extraction process.
- Physical Specifications
- Certificate of Analysis
- SDS
Product Specifications:
CAS#:593-84-0
Formula Weight:118.16
Molecular Formula:CH5N3-CHNS
Purity:Min. 99.0%
Melting Point:118-121° C
Solubility (70% H2O):Clear, haze-free
A280 (70% H2O):Max. 0.8
A300 (6M H2O):Max. 0.1
A410 (6M H2O):Max. 0.1
Molecular Biology Specifications:
DNase assay:None Detected
RNase assay:None Detected
Protease assay:None Detected
Certificate of Analysis Links:
CofA IB05100 - Lot#23D1004